We provide state-of-the art diagnostic pathology services.
Quality Laboratory Service for Today’s Clinician
The Centers for Medicare & Medicaid Services (CMS) regulates all laboratory testing (except research) performed on humans in the U.S. through the Clinical Laboratory Improvement Amendments (CLIA). In total, CLIA covers approximately 254,000 laboratory entities. The Division of Laboratory Services, within the Survey and Certification Group, under the Center for Clinical Standards and Quality (CCSQ) has the responsibility for implementing the CLIA Program.The objective of the CLIA program is to ensure quality laboratory testing. Although all clinical laboratories must be properly certified to receive Medicare or Medicaid payments, CLIA has no direct Medicare or Medicaid program responsibilities.
The College of American Pathologists (CAP’s) Laboratory Accreditation Program accredits the entire spectrum of laboratory test disciplines with the most scientifically rigorous customized checklist requirements.The CAP’s peer-based inspector model provides a unique balance of regulatory and educational coaching supported by the most respected worldwide pathology organization. The Laboratory Accreditation Program inspects a variety of laboratory settings from complex university medical centers to physician office laboratories, and covers a complete array of disciplines and testing procedures.
At Nova Labs, Zeiss Axio Microscopes are used to provide state-of-the-art magnification and display for our pathologists. Our reflected light microscopes feature AxioVision technology to provide the highest standard of magnification available.
Furthermore, Nova Labs is the only reference lab to be using Zeiss AxioScan.Z1 technology! providing fast and reliable slide scanning. We are able to digitize your specimens and create high-quality virtual slides.
ThermoFisher Scientific Technology… Coming soon!
About Small Fiber Neuropathy
Small-fiber neuropathy, also known as small-fiber sensory/peripheral neuropathy, is a peripheral nerve disease that selectively affects small diameter nerve fibers. These fibers innervate the skin, and aid in temperature perception, nociception (pain), and autonomic regulation. Common symptoms with peripheral neuropathy include:
· pins and needles
Skin Biopsy to Diagnose Small Fiber Neuropathy
Performing a skin biopsy to analyze and quantify nerve fibers in the epidermis is a relatively simple and convenient way to identify and monitor small fiber neuropathies. Studies support the high sensitivity and specificity city of skin biopsy in detecting small nerve fiber loss and it has been used not only in diagnosis, but also to evaluate disease progression and treatment success. ENFD studies have been found to have 88.4% sensitivity in detection, compared with 54.6% for clinical exam alone. Moreover, the test can detect early nerve fiber damage even in asymptomatic patients.
What can skin biopsies detect?
• Abnormal epidermal nerve fiber innervation
• Severity of neuropathy at sites not easily tested through electrophysiology
• Abnormal nerve fiber morphology which can predict development of neuropathy
• A pathological alternative in settings where electrophysiology is not available. Distinguish neuropathy from other causes of pain.